Below, we’ll walk you through the entire diagnostic process step by step, explaining how to identify the right symptoms, interpret biological samples, and conduct on-site investigations. We’ll also include a complete list of diagnoses for all patients. This way, you won’t have to rack your brains at all—simply find the right patient, open the tablet , and enter the correct disease. Then you can focus on other aspects of Pathologic 3.
How to diagnose patients in Pathologic 3?
To successfully identify the disease, follow this approach:
- Begin by carefully collecting symptoms . Carefully examine each patient: study dialogue options, pay attention to their portraits and compare them to their current appearance—they may show any skin discoloration, rashes, or lesions—and be sure to conduct a physical examination. After you’ve noted the suspected symptoms in the chart (press N), discuss each one with the patient. Symptoms that trigger additional dialogue options are considered confirmed and deserve special attention .
- Narrow down the range of possible diagnoses . Once you’ve collected all the available symptoms, compare them with known illnesses. If only one illness fits the list of symptoms, you’ve likely found the correct answer. However, more often than not, you’ll have to choose between several options.
- In ambiguous cases, use biological samples . When two diseases have similar symptom sets, biological analysis is essential. It’s important to determine which organ systems differ between the suspected diseases. The information panel for each disease indicates which organs are affected by the given diagnosis and which remain healthy.
- Follow prompts for investigations outside the hospital . Some diagnoses cannot be confirmed by clinical examination alone. Patient dialogue will indicate when further investigation is needed, and a marker will appear on the map indicating the location where you should definitely go and examine the patient. These forays can help you discover new symptoms or rule out false leads.
Day 4 – 3 patients
Patient 1 (Lyuta)
Inspection:
- Chest: pale
- Hands: bruises/hematomas
Symptoms:
- Heat
- Hematomas
- Severe pallor
Diagnosis: Anemic vasculopathy.
Patient 2 (Shchur)
Inspection:
- Chest: peeling skin
Symptoms:
- Headache
- Rapid pulse
- Eczema
Diagnosis: Burning (fever).
Patient 3 (Filat)
Inspection:
- Back: redness/rash
- Legs: damaged veins
Symptoms:
- Weakness
- Vein damage
- Redness of the skin
- Nausea and vomiting (when examined at home)
- Headache (when examining his home)
- Heat (when examining his house)
- Bulimia (when examining his home)
- Hydrophobia (when examining his house)
Note : In Filat’s case, to diagnose him, you must tell him to search his house—this way, you can learn more about his symptoms (ask a neighbor for the key to his room). You’ll have to travel to another district, but this is the only way to accurately diagnose the illness yourself.
Diagnosis: Mouse fever.
Day 5 – 3 patients
Patient 1 (Oktay)
Inspection:
- Breasts: Hardened skin
- Hands: peeling skin
- Legs (back): inflamed skin
Symptoms:
- Photophobia
- Stone disease
- Slow Pulse (will be revealed when talking to the Herbal Brides)
Note : It’s worth talking to the herbal brides waiting at the hospital to learn more about Oktay’s symptoms – they’ll tell you things he won’t tell you, and this will help narrow down the diagnosis.
Diagnosis: Lithiasis dermatitis.
Patient 2 (Bobok)
Inspection:
- Chest: abrasions, bruises
- Back: bruises
Symptoms:
- Lesions of the lips (visible on the face during the first questions)
- Headache
- Loss of coordination
- Heat
- Memory lapses
Diagnosis: Burning (fever).
Patient 3 (Smart)
Inspection:
- Chest: bruises
- Back: bruises
- Hands: bruises, hemorrhages
Note : In addition to the normal examination, press the Q key and focus on the patient to identify additional symptoms that are not visible or verbalized by the patient.
When you work with this patient, re-learn the basics of using a microscope to capture the specific symptom.
Talk to the patient after the examination and ask about the cough, then tell your Harruspex that there’s a task for them. Follow Daniil Dankovsky’s dialogue instructions, then take a sample. Head to the microscope and use it (as in the Prologue) to find a red cell.
Symptoms:
- Cough
- Chest pain
- Weakness
- Difficulty breathing (after taking a lung sample)
Diagnosis: Consumption.
Day 6 – 4 patients
Patient 1 (Zhitochnik)
Inspection:
- Hands: damaged veins
Symptoms:
- Chest pain
- Hallucinations
- Difficulty breathing
- Vein damage
Diagnosis: Ink syndrome.
Patient 2 (Lun)
Inspection:
- Breasts: extremely thin/sickly appearance
- Back: rash
Symptoms:
- Abdominal pain
- Nausea and vomiting
- Heartburn
- Rash
- Geophagy
Diagnosis: Steppe gastrodermal fever.
Patient 3 (Gannet)
Inspection:
- Chest: pale skin
- Hands: bruise
Symptoms:
- Weakness
- Chest pain
- Visual impairment
Diagnosis: Bradycardia.
Patient 4 (Burduk)
Inspection:
- Chest: pale, thin
- Back: bruises
- Hands: bruises
Symptoms:
- Redness of the eyes
- Heat
- Headache
- Cough
- Lack of appetite (after taking a sample from the gastrointestinal tract)
Note : A sample must be taken and examined under a microscope to determine a definitive diagnosis, as the symptoms are consistent with two conditions. It is recommended to take a sample from the gastrointestinal tract to determine the cause of the loss of appetite (the reagent can be found in containers near the microscope).
Diagnosis: Influenza.
Day 7 – 3 patients
Patient 1 (Emilia)
Inspection:
- Chest: thin
- Hands: scratches
Symptoms:
- Photophobia
- Visual impairment
- Weakness
- Dystrophy
- Bulimia
Diagnosis: Bonkowski fever.
Patient 2 (Funnel)
Inspection:
- Hands: peeling skin
Symptoms:
- Lesions of the lips
- Diarrhea
- Loss of coordination
- Difficulty breathing
Diagnosis: Pulmonomucosal syndrome.
Patient 3 (Tuutoi)
Inspection:
- Chest: scratches/cuts, uneven skin tone
- Hands: Vein damage
- Legs: vein damage
Symptoms:
- Darkening of the capillaries of the eyes
- Irregular pupil shape
- Vein damage
- Cyanosis (after sampling)
Note : A sample may need to be taken and analyzed to confirm the diagnosis. A lung or skin sample is recommended.
Diagnosis: Ink syndrome.
Day 8 – 3 patients
Patient 1 (Astrild)
Symptoms:
- Redness of the eyes
- Redness of the skin
- Fever
Diagnosis: Measles.
Patient 2 (Chernyak)
Symptoms:
- Redness of the eyes
- Sore throat
- Ichthyosis
- Joint pain
- Rapid pulse
Diagnosis: Tabes.
Patient 3 (Miros)
Symptoms:
- Nausea and vomiting
- Headache
- Weakness
- Fever
- Insect bites
Diagnosis: Tularemia.
Patient 4 (Petrel)
Symptoms:
- Nausea and vomiting
- Rash
- Difficulty breathing
- Insect bites
Diagnosis: Steppe gastrodermal fever.
Day 9 – 4 patients
Patient 1 (Aristarchus)
Symptoms:
- Dystrophy
- Weakness
- Nausea and vomiting
Diagnosis: Hepatitis.
Patient 2 (Sah Man)
Symptoms:
- Hallucinations
- Headache
- Photosensitivity
- Vein damage
- Memory lapses
Diagnosis: Tvirin syndrome.
Patient 3 (Poshinok)
Symptoms:
- Redness of the eyes
- Redness on the skin
- Fever
Diagnosis: Measles.
Patient 4 (Sergeant Dodo)
Symptoms:
- Redness of the eyes
- Headache
- Fever
- Severe pallor
Diagnosis: Anemic vasculopathy.
Day 10 – 2 patients
Patient 1 (Yakov Tochechka)
Diagnosis: Snake syndrome.
Patient 2 (Kira)
Diagnosis: Acute bronchopathy.