Grace Ashcroft’s gameplay sequences are filled with horror elements and tension. This is particularly acute in the basement beneath the Rhodes Hill Medical Center, where you’ll find yourself after the events in the isolation ward to rescue Emily. Navigating this location is challenging, and the presence of the Girl doesn’t make things any easier.
As you explore the underground complex, you’ll eventually descend into its murky depths. This mini-guide will walk you through all the content you’ll encounter in the medical center’s basement.
The map above shows the key items and collectibles you can find in the Medical Center basement. There are plenty of useful finds here, including Mr. Raccoon figurines, documents, inventory upgrades (hip pouch), health and damage boosts, as well as lockpicks and crafting materials
Note : There is a save point and item storage in the security room.
Medical Center Basement: Main Targets and Enemies

Your main goal in the basement is to free Emily. To do this, you need to find three connector plugs and install them in the main terminal at the end of the corridor with the containment cells . However, this task is complicated by several factors:
- Many infected appear “dead.” However, at certain moments or under certain conditions, they can revive. It’s up to you to decide whether to finish them off later or use hemolytic injectors while they’re lying on the floor. Or, save your shots and try to sneak past them. If you hit someone or shoot them, the infected will rise. As for the infected in the cells, only one poses a threat. At a certain point, he’ll break free, but this will also allow you to find an empty injector in his cell to craft stabilizers or steroids.
- When you pull the connector plug, power to the corresponding section of the basement is cut off. You’ll have to decide which generators to power next to continue exploring the area.
- The Girl hides in various rooms and most often appears in dark places. With the exception of the security room, only areas where you’ve restored power using plugs and generators are considered safe zones. To scare off the Girl, you need to reach the nearest generator, insert a plug, and wait for her to flee the illuminated area. Otherwise, if she catches up with Grace, she’ll eat her.
Part 1: Containment cells, workshop and inspection room
Here’s what you need to do after gaining control of Grace in the basement of the Resident Evil Requiem Medical Center . Pick up the document “Employee’s Last Words” lying next to the corpse. Head to the security room and grab the file “Operation: Girl’s Elimination.” Save your game. Also, leave any unnecessary items in the storage room—you’ll need the extra inventory space.
Proceed through the Furnace area and the Containment Chambers to trigger a cutscene. At the end of the corridor with the Containment Chambers, you’ll see the main generator, which requires three connector plugs. It already has one plug installed, so take it. If you examine the schematic nearby, you’ll receive the file “How to Open the Containment Chambers.”

Avoid the Girl and install the connecting plug into the generator in the Furnace area. Explore the security room and pick up the file “Locksmith’s Note.” Open the safe using the combination: right to 60, left to 40, right to 80. Inside are pistol ammo and a map with the locations of all Mr. Raccoons in Rhodes Hill (both in the medical center itself, in the basement, and beyond).
Examine the forklift and remove the connector from the generator near the security room. Climb through the ventilation shaft next to the forklift to reach the workshop. There you’ll find a lockpick, the “Security Guard Report” file, and a Mr. Raccoon statue.
Note : One of the small rooms in the containment cells contains an empty injector, allowing you to create a health or damage boost. The cell will be unavailable until you return from the security area a little later.
Part 2: Boiler room and sleeping quarters
Next, take one of the connecting plugs—preferably the one used to open the path to the workshop—and bring it to the first corridor past the security room with the save point. This generator will power the boiler room and the sleeping quarters.
In the bedroom, smash another Mr. Raccoon collectible figurine, as well as a document with a crafting recipe. There’s also a lockbox here that you can open with a lockpick to obtain a rare metal—a material for crafting Requiem ammunition. If you go into the boiler room across the street, you’ll notice that all the loot is in water, and the puddles are electrified. Don’t go into the water right now!
Remove the connecting plug from the generator in the hallway next to the boiler room and sleeping quarters and take it to the northeast part of the basement—near the hole Grace jumped through to enter the area. Move the crate and squeeze through the gap. Pick up the lockpick lying on the floor. Go to the opposite side and grab the socket wrench. Afterwards, the Girl will emerge from the ceiling and begin gnawing on the corpse near the hole in the grate.

Throw the empty bottle and, while she’s distracted, squeeze back through the gap. Or wait and go around the Girl when she starts patrolling the room. On your way back, the Girl will emerge from the ceiling, giving you time to run into the safe security room.
Part 3: Collection basin and “Recycling” area
To access another section of the basement beneath the medical center in Resident Evil Requiem, you’ll need to bring two connector plugs to the blood collection pool. Install them in the generator by the pool, after using the socket wrench to open the cover. Climb through the shaft. It will lead you to the “Recycling” area, which is divided into two sections by a pool of bloody sludge.
There’s another connector plug in the first area, but you can’t remove it yet, as doing so will block the exit. Well, you can, but you’ll be trapped. Instead, pick up the forklift key from the floor near the corpse and use it to enter the small room ahead. Inside is a basement map, as well as a hip pouch upgrade for Grace.

With the forklift key, leave the Recycling Facility and return the same way. Be prepared for a few unpleasant surprises. Don’t forget to pick up the two connector plugs from the generator by the blood pool again.
Part 4: Return to the Security Room
Now your goal is to return to the inspection room. Don’t take the path through the Furnace. The girl will appear in the main inspection room and can grab Grace. Instead, return through the workshop area at the end of the containment cells. Be aware that on your way to the workshop, one of the infected will break open a containment cell. Inside this cell is an empty injector.
Install one connector plug into the generator near the workshop, then crawl through the shaft leading back to the security room. In the security area, wait until the Girl turns away and leaves. Then, install the second connector plug into the generator at the entrance to the security room to turn the lights back on.

Next, use the forklift key to enter the room with the hanging corpses. There’s also another locker here containing a rare metal, which can be opened with a master key (immediately to the left as you enter the room). As the hanging bodies move from left to right, follow them along the right wall and into the center of the room. The hanging infected will try to grab Grace, but this has no effect.
Push the crate to create a path to the control lever. Then flip the lever to change the direction of the bag and corpses—they will now move from right to left. After that, walk back between the shelves where you removed the crate. Proceed deeper into the room and exit into the “Recycling” area.

Part 5: Return to Recycling
You’ll eventually find yourself on the opposite side of the Recycling Chamber. Save your game before draining the blood from the pool. Note that this location is connected to a rather difficult challenge— the secret puzzle “The Final Riddle . “
When you’re ready, drain the blood from the pool and jump down. There’s a huge meat grinder on the opposite side, so try to stay away from it. Fight off the infected that will randomly revive. You can stun them and push them to the floor, and the spinning blades will do the trick. When the battle is over, climb the ladder and grab the third and final connector plug.
You won’t be able to exit through the security room with the hanging corpses, but there’s another ventilation shaft near the typewriter (save point) and the valve. This shaft leads to the bottom of the blood pool, and if you lower it, you can collect a lot of infected blood for crafting. This will help you complete the “Bloodlust” challenge, which rewards a whopping 10,000 RP. Take the elevator back to the main area with the blood pool, then return to the security room to save.
Part 6: How to Escape the Basement
It’s time to escape the medical center basement in Resident Evil Requiem. Save your game, because you’re approaching the point of no return. When you’re ready, follow these steps.
Place the connector plug from the “Refinery” area into the generator in the “Furnace” area, but don’t go through the tunnel. Instead, use the shaft in the workshop that leads back to the entrance to the inspection area. Remove the connector plug from the generator near the inspection room. The girl will suddenly appear behind you, on the path between the inspection room and the ventilation shaft that leads to the workshop. So, immediately run back to the “Furnace” area. Take the second connector plug from the generator in the “Furnace” area. Then go around and return to the workshop generator to get the third connector plug.

Go to the end of the containment chambers and insert all three connector plugs into the device to trigger a cutscene. Grace will free Emily, but that’s not the end of it. Immediately after the cutscene, run straight ahead and turn left just before a pair of infected. Run through the Furnace area, past the security room, and head to the glowing elevator at the end of the hallway. Perform a quick button press sequence to push the wooden planks (look down at the planks). Shortly after, another QTE will begin, requiring you to open the elevator door. You need to press the same key/button. If you fail these QTEs, the Girl will grab Emily or Grace, leading to a Game Over screen.
If you successfully complete all the QTEs , Grace and Emily will escape the basement. The objective of rescuing Emily is complete. Note: on the floor near the elevator, you can see an item called “Severed Hand,” which is actually part of the challenging puzzle “The Final Riddle . “